Oncologist

Just a general principle question. In anal cancer metastatic to liver, I used carboplatin and paclitaxel with good responce after 6 cycles. How long can you continue these chemo? Is there a limit to number of cycles? Or role of chemo holiday? Going to one of the chemo? Or stopping after certain fixed amount of cycles?

GI Cancer Specialist

There is no specific limit to the amount of chemotherapy. I would use a chemo holiday or holding a drug as indicated by tolerance. In one of the pivotal trials, the medial number of cycles was 5.5, so I think your patient is doing well and I would continue the regimen.